Efficacy:

1 Function: hawthorn expand peripheral vascular and have lasting antihypertensive effect, especially for cold-blooded

antihypertensive effect of longest, when hawthorn should share the soup, and greatly enhance its antihypertensive effect,

and the action time is extended.

2 Against myocardial ischemia: hawthorn flavonoids can alleviate myocardial ischemia-reperfusion injury of ecg ST

segment changes, increase the serum NO concentration, reduce the myocardial ischemia reperfusion myocardial tissue

malondialdehyde (MDA) level. Hawthorn polymerization flavonoids can rabbit experimental myocardial infarction narrow

scope. Literature reports, hawthorn extract can inhibit ischemia-reperfusion (LDH) in serum of rats, enhance the vitality of

SOD, reduce the generation of MDA, thus protecting myocardium, reduce myocardial cell injury caused by ischemia-reperfusion.

3 Adjusting blood lipid: hawthorn flavonoids showed a significant regulating blood lipid, the blood vessel function injury in

rats caused by hyperlipidemia has obvious protective effect, with hawthorn match definitely zhi-qian Chen wu decoction in the

treatment of dyslipidemia patients 65 cases showed that TC, LDL - C declined significantly after treatment, compared before

and after treatment, all have very significant difference, the significance of its 89.2% efficient.

4 Anti cerebral ischemia action: hawthorn leaves flavonoids can obviously improve the model of LDH and SOD

vitality in mice, game focal cerebral ischemia reperfusion injury in mice brain tissue has obvious protective effect,

its mechanism is related to the antioxidant.

5 Effect on blood rheology: hawthorn flavones three doses (80, 40, 20 g/kg), acute blood stasis model rats

were lower than whole blood viscosity, plasma viscosity and erythrocyte deposited of promoting blood circulation

to remove blood stasis. Hawthorn alcohol extract of middle and low cut had significantly lower than the whole

blood viscosity role.

6 On vascular endothelial cells: role of low density lipoprotein with different doses of hawthorn on oxidation

induced human umbilical vein endothelial cells (EC) showed that the damage and direct effect on EC, hawthorn

can inhibit the oxidative modification of low density lipoprotein, reduce the formation of lipid peroxides, blocking

the production of harmful substances by the direct effect on the endothelial cell, regulating endothelial function,

enhancing the resistance of endothelial cells on the harmful factors and tolerance, to protect endothelial cells from damage.

7 the digestive system function: hawthorn can single application, also with the divine comedy, malt, radish seed,

such as compatibility, strengthen the disappear of the work product. It contains vitamin C, vitamin B, carotene, and a

variety of organic acids, oral can increase the secretion of digestive enzymes in the stomach, contained protease, fatty

acid, can promote digest meat decomposition.

8 Sugar metabolism and antioxidant effect: 6% hawthorn water decoction can obviously reduce the high fat diet

rats fasting serum insulin and MDA level, indicates that it can improve the high-fat diet rats insulin hematic disease,

strengthen the body resistance to lipid oxidation, the mechanism may be related to regulate sugar metabolism, its

efficacy material base may be associated with st John's wort and ursolic acid.